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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c223e7793ba21b85a41bbc9b37e7b777df4b164789754e04c350a41727b008e9' 
  AND token = 'Iv/MYxyVR30YCCP1oh6eCEiUjMc6V6KL20Ko3IucOAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}