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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c77186a745d2626ca6d01403c7a038698c060e5362f55cd3df12391185dca381' 
  AND token = '3b9EjkiAzXW7OEX8xx5iN6xPAlOgyLCRyWqvNSaRykQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}