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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258e90a5ec4d15e21881404a8225f0b4fe6c308e6d2267589fbfd0d418a4f2bf' 
  AND token = 'yJqs3D6TI/uOzSxbMiXLEp23ZdddqB598V1NnG3PwnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}