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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6cb58b9d23aece0e7c43da8809444001c50457df47b3bb07b21f84693a80e33' 
  AND token = '6KgLxnrhZj87jlG9liAEt+Wx6z4hhN1AHu+8FspTCFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}