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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcc1f744ba003fce3a2f5e47d20011aaa0f9a3d718dc4d6aae854e8120e9b9a6' 
  AND token = 'MouuqAIEJ6ecqMFet6XD6L0tyhnVUVmMx3VSD8fSd+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}