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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6603be54914771925f5b9284d951b0304594d374e88804b4d5a939832da0be46' 
  AND token = 'AInCOm3Zp9GSnDwAAuuBRuE6/gonm1rV3QzuAZUIDBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}