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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eccf7e13ae223a3751cf685ecf4dee752ff21069bc1f5e7cac8735ebefd410b' 
  AND token = '61wA29VshDuzNduaqPAt31SgkJmuWEaPDjUF7FHss7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}