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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e1a1536f888d1b1a708b3456ef480eb20b13270ed26c79cf366fa57b0ee903a' 
  AND token = 'pIWTN0KebTZ4fQd9WCLjUSi2olM/9UkgRBLlHJS2urg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}