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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e35eba80f2cd7fb9ca7609cb1cb1eabf61ffcf4c2d0f43555fc3de894ada30' 
  AND token = 'z64z2WBeQ+fuw+5+qAUe21S0GBSw3VFzubK35qeaW2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}