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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4a7dbf1a46f7e92d5a4c9b5ec5a52bc07bc53b5df60127b41dc70b2ab1bcdb' 
  AND token = 'Ho6zxNu3LVzb+KNJx4POKuocdIDo8Hpy9+/xT52P7GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}