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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b00e506b043ef816aea864b7161187f9839b3224e1654b6969b26c494b634d5' 
  AND token = 'AwoAn0vwskr/yqVzXVvFOFyF3vFrenGqQAOkxsQy5nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}