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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00eca7a333a1d21271092010ad64277c51943ef33aa6291004a2454396c4568f' 
  AND token = '1PhB3di1NHlLZz842JyWrreO4X9yoVUeoULvud977T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}