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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59ef1758468f559a8ee979ea2f6f93837f7cfda8d3cae6771130e73c86e71a7' 
  AND token = 'SwLlzu5P1TwFjYik+xPCR2IjzE6wY2F4kDBmWIWgFRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}