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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6cf36641b571e81703deeaf0eea357c7c6d2134f245ddcc1e2ca3039d939937' 
  AND token = 'a2/hljHS03B0WT2jk8mVOtqQYiwHUm1vx/9fbO2AR2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}