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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4839427e7e87978cb182e3542916bcc3864e974580dd9fac9e53c737195d156f' 
  AND token = 'FCrzYO1sXo2WAvW62OOVk1OGqYoKF3jfbzWMs5U8Ob0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}