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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2b78a81fb107fc6c8b790613cd0584ce6bc3aa858d88aeeeba9d896892a2f3' 
  AND token = '6SzMUn05Qvuginsj9XM0++2jds4YTQ6DydLHXMVyV/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}