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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4bc0948adbb400084d847e87e627494f99fd2fa18b5a9085c7ee6160e4a9fe' 
  AND token = 'Smb3c1bDL/X9t2UD/zd2t8wE/AJCKb+s2kh9ORSqXeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}