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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eecfcfa540ad173417e09a82a56cb2f853226ae8375cab4ebe71cb5ee18fc4f8' 
  AND token = 'u2gFmW6//2VyS8gw9AQbCklMj5NNFrg0yH0zqpeZ+EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}