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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162a3299d4bd086654ea2bb9b590a52e8e9ea37974afdfadbf92a84a8997c4cb' 
  AND token = 'xm+FRbySACVBa8WCEZoBbhFk6Naaj0B4qFaWrNCSoOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}