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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '064e11d9a86fd066e41ae0fc183ce44153a5ba8a407b746ebbb046ba19784f33' 
  AND token = 'MtxBKDHZ5IcUwnGUhaYxj/6lvcGPaNkMhDDYqQAwY9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}