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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee380051f55023eabfb06ed1f885b67503d6736171166acc4d312e98cbff2e0f' 
  AND token = '1LKKJ2u+X4Y4Ppnob2Gnqa8pd/vOQxVK59Ta+9Kue2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}