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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64639bcc1eae1d2bbc99b9cc51dc6cfce9ef6effc94cf04d9a36fc3caefbe757' 
  AND token = '9WM1pNY3lbV9HMA5wMleEnGDFwLa3qbzZSOBdX/46WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}