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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76d8b47601009659db1e7efcf65195c4f67c5b15a101a4590568ef4fd47d9249' 
  AND token = '4rkEtLK21zKlEnUYjikDWxSVJng4EK2j12C4zzQwr28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}