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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e541f1670805c68883281ef1bcee5bb84d4e41fb65870017dc9e5298c1768595' 
  AND token = '8NvGL1iQ0aJKS0fgl5H9GGzwcx9F0PRGeqGRVCG3SHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}