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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dcb4833c72507189409bd201b66da8aa1cba0dbfc9c65fd7680195ef52d9cf4' 
  AND token = 'ki4+O2DGWuNjwQWOrEluIKtGHNCjZp0wtpQ9wWGuj70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}