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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c06cfea8c2741c45778fc9897352a6d20b5e3d357f92c7d10bc18b10d6af618' 
  AND token = 'CT79CM5kg0/SzC/d1ZQ/n6dwdYSnnLgVGiOMFgtG24o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}