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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22db781b10e30ed0f8d755dd4d6993fc11c052fc3757d604e27b5bcce07b0b35' 
  AND token = 'akIjERXns1HSjt6Xmxo2mh0gU37uVyZwdOrzzb/lXEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}