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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38acdbdf0b64629e80eecee713b4b4d3c2ad08298f3811d53700019d855d0fa7' 
  AND token = 'xTK4h59i0ggPZIEsKUjAPmpQyj6HmXwEmY+xb6M4Rds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}