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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee78fbd64ecd3cbfd8eae8af2d29e457169f1d790a5b90dec11912e340b4433' 
  AND token = 'T4I0FD/zp64auW/2sAARWJ6nt3wn2xgraJf2hKWUytk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}