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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cc4c08d4f05e79f93ea5084f423d28d1632000503f5a4fac12570fa05b61e00' 
  AND token = 'IAm3XFWrrxHa9c1fhbZdG/+KeTZBI2/cwRKwOHx9F84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}