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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76f8275232730dea3b9c16e345557cc527c34b9b15ef7eb1aa53e10521ccc64e' 
  AND token = 'qE1wNjMU5Vq1QNQ7HKjurBfbkLEfeQRTTrQKQTXPMHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}