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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d42256df96702a6ef2d4e8c9527233fea2a10aa6fca1f62d7c4b11b1f8c3b3b' 
  AND token = 'iSzUJ1whyr2T9rWV3WqKiHR/LgatnrtEZJ2vgHvaJRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}