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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61f0f383ed8a39cc019d4f065ff5b0b7d654dfdba69b45bf3aca64a7694ffdb2' 
  AND token = 'GE0fJbzDwlWkrj3h93lsRNkc8rCNutTZMAdUCjjBBzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}