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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea6332d0e781119ac2e053682c1fde4a402bc81e02c1c18b4a18a3311e3284c7' 
  AND token = 'HOLMLDblZLMsc7sAVImnDrRKEnaD6u/tAhRSXH3WTrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}