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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f3baefeb21771d7ca44b9bc7f97fff57af90408be69cabea545043d7391609' 
  AND token = 'okJl6xoD8XvVXdnE1ZmRSfTBcj0Qz/NFwZ4xnmUyP6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}