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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e149f02f6a2bae7705384e78a9c6f890b2e709144d8947fd7979243fe9bd3cf4' 
  AND token = 'yrKSiN5uZd457IZ5XZ8/4sD/7a/8GRbSg5DoQ6kM3CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}