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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7405b6616abbe73edf20b4d2bd5b97257c5766fe28aeda4de037d4f70a3281a6' 
  AND token = 'QXsAIP8088G8MwMexLbQFwJL5ANVg7jIt+7CCEg/qI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}