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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494699a11763bb7748ec1336adc4ecb9bb018275ccff419036c4417f593f7b39' 
  AND token = 'Tb6TMd4PhMzSD+Ca6IgDM+6j0ed56TtJ3BWfkBLX9xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}