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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168899f1ab7d57c91ac5193c9f98ce6f7dbbaa3d3a2175cdd49b84d7fb5277a4' 
  AND token = 'aTCqd2f/fH+ha3R+LPgxoW4I0CKm8TAl0IvuKKaGD3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}