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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eebe5a5c47fbd2c8c7247600452e89de9a68a336de076f0e7d6867e554dad53' 
  AND token = 'u3L3pJCpGBTJJ92Ea441VsnChChkGtUl5jLSsB0A1iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}