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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a8a192f3f97ac4b110ac41ccd62a71cbb779fc8238c6e339e253aed97eed09' 
  AND token = '8ukAFFOHay07xqTtD1lXiX44lot0l6TutKL1dFcS/Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}