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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a16f4472b14df9c1b15ef285662178f43e8dfa619b1bee16f1a9f8d5196074' 
  AND token = 'oXq6OThLJUi5NZOo17UAFuEinG+/rx1TH1yLAxhD9EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}