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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708443eab9c0f2025754dbbf7382952f4a01994907dd948ec97a416eb3f77551' 
  AND token = 'v0Duc4Y7urz8APvDgg3MoMTN6QAEoo2fkT5Vx/vIyMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}