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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ff6676933fc0e3059b26921765000f33a64104de8c8c194889e70d90b68e19' 
  AND token = 'pXPxkjIbrQ7Gc8de2Arh55SlJTP2OnA/h+1FeBqbhDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}