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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d0b392f756c287a046022ea5d31861b99575c27407224ff3cfcfed01ae3ed8' 
  AND token = 'XhC6V4NA1+uk0j3txCmorUM2jQnoW3ptufb0eJ8Cqqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}