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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6424f6ed97aef7a5f1d62b602a932c59465475078bfe8fac1e53de9024b5d09e' 
  AND token = 'UuBht+XASrBnUTT9ZnQZDAwzvyy1ZcSlOcuQVdQSHzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}