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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7722cb0fa6a3ef56374f3d8d78b1606088b44c808f321b04b723fdfb6f40801d' 
  AND token = 'AOMxbYlBnJf1i29N59wzCkGCfllr9VXrnKIVQUT9ZuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}