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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2213cae5454fbd51c6b354d4dcecaad1c261bb5a5b1ebcad6bce9a9af7bdc385' 
  AND token = 'tnE1rniQ01OmQUK0+M2UWac8RzrrXEjkPnBaBfMKFHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}