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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ada2efe9a786cda3f9ea7622a249f5f131cda3d96fe6c04f7c5f9b50cd8a42d' 
  AND token = 'elTBB9BAG8S6ePQYdwdWbf7V/5cbonoug/pEkWeoqT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}