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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b15f82f23212f86f88ee6fa4199edd876b20f7a18c34d8ffd669f910092f57b' 
  AND token = 'auAoraG8TAeb3beIhUNFzUox6VKm1Go+EkVeS7HnNy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}